El-Naggar, A. M.’s team published research in Afinidad in 44 | CAS: 10543-42-7

Afinidad published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, SDS of cas: 10543-42-7.

El-Naggar, A. M. published the artcileSynthesis and antimicrobial activity of some new N-coumarin-6-sulfonyl amino acid and dipeptide derivatives, SDS of cas: 10543-42-7, the publication is Afinidad (1987), 44(411), 431-3, database is CAplus.

Title amino acids I [X = β-Ala, Val, DL-Val, Leu, p-NHC6H4CO (p-Aba), m-NHC6H4CO (m-Aba), Tyr, etc.] were prepared by sulfonylating the appropriate amino acid with sulfonyl chloride II. I were esterified with MeOH via SOCl2 to give the corresponding Me esters. Dipeptides III (X-X1 = β-Ala-DL-Ser, β-Ala-Leu, Pro-Phe, Phe-Val, etc.) were prepared by coupling the appropriate I with H-X1-OMe.HCl by DCC in THF containing Et3N. I (X = β-Ala, p-Aba, m-Aba) and the Me esters of I (X = Leu, Pro) were active against a number of microorganisms.

Afinidad published new progress about 10543-42-7. 10543-42-7 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Chloride,Sulfonyl chlorides,Ester, name is Coumarin-6-sulfonyl chloride, and the molecular formula is C9H5ClO4S, SDS of cas: 10543-42-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics