Ruso, Jayaraman Sembian published the artcileAntimicrobial activities of novel 3-substituted-[1,2,4]triazolo[4,3-b]pyridazine derivatives, Application In Synthesis of 93118-03-7, the main research area is triazolopyridazine preparation antibacterial antifungal.
A novel derivatives of 3-substituted-[1,2,4]triazolo[4,3-b]pyridazine I [R = 3-C6H4Br, 2,6-C6H3Cl2, 4-C6H4COOH, etc.] and 7,8,9,10-tetrahydrobenzo[4,5]thieno[2,3-d][1,2,4]triazolo[4,3-b]pyridazine II [R1 = 3-C6H4Br, 2-C6H4CF, cyclopropyl, etc.] were prepared by the reaction of heteroaryl hydrazone from the aldehyde and pyridazinohydrazine derivative, followed by subjecting the intermediate directly to oxidative cyclization employing the mixture of Me4NBr and oxone. The derivatives I and II were subjected to preliminary antimicrobial activities against microorganism. All these compounds I and II exhibit good to moderate activity.
Journal of the Korean Chemical Society published new progress about Antibacterial agents. 93118-03-7 belongs to class chlorides-buliding-blocks, name is 2-Chloro-3-(trifluoromethyl)benzaldehyde, and the molecular formula is C8H4ClF3O, Application In Synthesis of 93118-03-7.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics