Dubost, Emmanuelle published the artcileGeneral method for the synthesis of substituted phenanthridin-6(5H)-ones using a KOH-mediated anionic ring closure as the key step, Recommanded Product: 4-Chloro-2-fluoroiodobenzene, the main research area is fluoro arylboronic acid preparation halo arylnitrile Suzuki coupling palladium; fluorobiphenyl carbonitrile preparation anionic ring closure potassium hydroxide microwave; phenanthridinone preparation; microwave irradiation anionic ring closure mediator; potassium hydroxide anionic ring closure mediator; palladium Suzuki cross coupling catalyst.
Substituted phenanthridin-6(5H)-ones were obtained in a two-step procedure involving a Suzuki cross-coupling reaction followed by a KOH-mediated anionic ring closure. The influence of the nature and the position of the substituents on the cyclization step were studied. This methodol. offers a general and practical route to diversely substituted phenanthridin-6(5H)-ones, e.g., I (R = H, F).
Tetrahedron published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent) (halo). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Recommanded Product: 4-Chloro-2-fluoroiodobenzene.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics