Xu, Jun published the artcileCoordinating Activation Strategy-Induced Selective C-H Trifluoromethylation of Anilines, Related Products of chlorides-buliding-blocks, the main research area is trifluoromethyl aniline preparation coordinating activation trifluoromethylation picolinamide.
A simple protocol for the synthesis of 2-(trifluoromethyl)aniline derivatives through a coordinating activation strategy was developed. The reaction showed good reactivity and gave the target products in moderate to good yields. Pleasingly, the directing group could be recovered in excellent yield. Furthermore, this strategy allowed efficient access to the synthesis of floctafenine. A single-electron-transfer mechanism was proposed to be responsible for this trifluoromethylation reaction.
ChemCatChem published new progress about Anilines Role: SPN (Synthetic Preparation), PREP (Preparation) (trifluoromethyl). 62593-17-3 belongs to class chlorides-buliding-blocks, name is 2,4-Dichloro-6-(trifluoromethyl)aniline, and the molecular formula is C7H4Cl2F3N, Related Products of chlorides-buliding-blocks.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics