On October 19, 1987, Fukuoka, Shinsuke published a patent.Quality Control of 4-Chloro-2-fluorotoluene The title of the patent was Preparation of aryl fluoroarenecarboxylates as intermediates for agrochemicals, pharmaceuticals, and polymers. And the patent contained the following:
The title esters, useful as intermediates for agrochems., pharmaceuticals, and heat-stable polymers, are prepared Heating a mixture of p-FC6H4Br 50, PhONa 60, and Ni(acac)2 2.5 mmol in MePh at 250° and 50 kg/cm2 CO gave 82% p-FC6H4CO2Ph. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Quality Control of 4-Chloro-2-fluorotoluene
The Article related to aryl arenecarboxylate intermediate agrochem pharmaceutical, polymer intermediate aryl arenecarboxylate, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Esters, Acyl Peroxides, Acyl Halides and other aspects.Quality Control of 4-Chloro-2-fluorotoluene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics