On September 10, 2019, Hong, Hao; Zhang, Enxuan; Lu, Jiangping; Liu, Zhiqing; Li, Chao; Tan, Yang published a patent.Recommanded Product: 452-75-5 The title of the patent was Continuous synthesis method of substituted benzoic acid organic matter by oxygen gas oxidation. And the patent contained the following:
The title continuous synthesis method includes reacting compound (such as 2,4-difluoroacetophenone) and oxygen gas under catalysis of catalyst (cobalt acetate, cobalt acetylacetonate, etc.) in presence of metal halide (sodium bromide, lithium chloride, etc.) and initiator (azobisisobutyronitrile, N-hydroxyphthalimide, etc.) in organic solvent (formic acid, glacial acetic acid, etc.) at 130-180°C and 1-2.5 MPa for 90-240 min to obtain the title compounds (such as 2,4-difluorobenzoic acid). The invention has cheap and easily available oxygen gas, no three wastes, improved utilization rate of oxygen gas, simplified operation, and improved reaction safety and product yield. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Recommanded Product: 452-75-5
The Article related to benzoic acid preparation oxidation acetophenone methylbenzene, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Carboxylic Acids and Peroxycarboxylic Acids and Their Sulfur-Containing Analogs and Salts and other aspects.Recommanded Product: 452-75-5
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics