Bujok, Robert; Cmoch, Piotr; Wrobel, Zbigniew; Wojciechowski, Krzysztof published an article in 2017, the title of the article was Transition-metal-free synthesis of 3-(1-pyrrolidinyl)quinolines and 3-(1-pyrrolidinyl)quinoline 1-oxides via a one-pot reaction of 3-(1-pyrrolidinyl)crotonates with nitrobenzenes.Product Details of 38939-88-7 And the article contains the following content:
A carbanion of tert-Bu 3-(1-pyrrolidinyl)crotonate added to nitrobenzenes to form σH-adducts, which in the presence of pivaloyl chloride and triethylamine were converted into 3-(1-pyrrolidinyl)quinolines or 3-(1-pyrrolidinyl)quinoline 1-oxides depending on the nitrobenzene structure. This was the first methodol. in which a quinoline ring was constructed from a substrate bearing a pyrrolidinyl ring. Starting from optically pure enamines, the method allowed synthesis of the corresponding chiral products without racemization. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Product Details of 38939-88-7
The Article related to tert butyl pyrrolidinylcrotonate enantioselective diastereoselective preparation nitrobenzene cyclization, pyrrolidinyl quinolinecarboxylate preparation, quinoline oxide pyrrolidinyl preparation and other aspects.Product Details of 38939-88-7
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics