On April 25, 2019, Sun, Shuai-Shuai; Chen, Junyou; Zhao, Rui; Bierer, Donald; Wang, Jun; Fang, Ge-Min; Li, Yi-Ming published an article.Product Details of 98946-18-0 The title of the article was Efficient synthesis of a side-chain extended diaminodiacid for solid-phase synthesis of peptide disulfide bond mimics. And the article contained the following:
Solid-phase incorporation of diaminodiacids is one of the most effective approaches for synthesis of peptide disulfide bond mimics. One of a limitation of current diaminodiacid toolbox is that only four-atom linkage mimics are available that may not fully meet the activity optimization requirement. In this work, we developed a new diaminodiacid that contains a five-atom thioether (C-C-S-C-C) bridge for the first time. With this diaminodiacid in hand, we successfully obtained oxytocin containing new disulfide bond mimic by solid phase peptide synthesis. The experimental process involved the reaction of tert-Butyl trichloroacetimidate(cas: 98946-18-0).Product Details of 98946-18-0
The Article related to diamino diacid synthesis solid phase incorporation peptide disulfide bond, oxytocin mimic cyclic peptide solid phase synthesis oxidative cyclization, homoserine protection sulfonation substitution hydrolysis bromination thioalkylation and other aspects.Product Details of 98946-18-0
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Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics