The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. COA of Formula: C7H8ClN.
Yang, Zhikun;Xu, Jiahui;Bai, Yumeng;Wang, Zhao;Duan, Liusheng;Tan, Weiming research published 《 Design, Synthesis and Gibberellin-Like Activity of Novel 1-Substituted 3-[3-(Trifluoromethyl)phenyl]thiourea Derivatives》, the research content is summarized as follows. It has previously been demonstrated that a thiourea derivative, namely 1-phenethyl-3-[3-(trifluoromethyl)phenyl]thiourea (Y21), exhibits high gibberellin-like activity. In this work, the influence of the alkyl chain length and various benzene ring substituents on the biol. activity of Y21 was investigated. 1-Substituted 3-[3-(trifluoromethyl)phenyl]thiourea derivatives were designed, synthesized, and comprehensively evaluated. The biol. activity anal. demonstrated that at a dose of 0.1 μM, compound S8, i.e., 1-(3-bromophenethyl)-3-[3-(trifluoromethyl)phenyl]thiourea, exhibited significantly higher promoting activity with respect to Arabidopsis thaliana hypocotyl elongation and rice germination than did gibberellin A3 (GA3) and Y21. Moreover, the physiol. response of the A. thaliana mutant ga1-1 to treatment with S8 suggested that this compound possessed GA-like function. The mol. docking anal. indicated that S8 formed hydrogen bonding interactions with residues Phe238 and Ser191 of the gibberellin insensitive DWARF1 (GID1) receptor, which resulted in stronger binding with GID1 than Y21. The bioactivity of derivatives S1-S22 exhibited a clear neg. monotonic association with the mol. docking-based score values. Overall, it was determined that S8 displayed excellent GA-like bioactivity and facilitated hypocotyl elongation and germination; therefore, it could be applied as a potential plant growth regulator.
104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., COA of Formula: C7H8ClN
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics