Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Product Details of C7H8ClN.
Udaya Kumar, A. H.;Mahesha;Pampa, K. J.;Kumara, Karthik;Hema, M. K.;Harohally, Nanishankar V.;Lokanath, N. K. research published 《 Structural-property relationship in halogen-bonded Schiff base derivative: Crystal structure, computational and SARS-CoV-2 docking studies》, the research content is summarized as follows. We synthesized the halogenated Schiff base compound to understand the influence of halogen and hydrogen bonding interactions. The Schiff base compound is characterized by FTIR, SEM-EDAX and single-crystal X-ray diffraction studies. The structural studies reveal that the 4-chloro-2-(((4-chlorobenzyl) imino) methyl) phenol crystallizes in the monoclinic, P21/n space group. The O1-H1N1 strong hydrogen bond forms the intramol. pseudo chelating ring motif and acts as a coordinating site for metal complexes. The intra, intermol. and ππ interactions were involved in the construction of supramol. architecture. The interesting type-I halogen bonds having trans geometry are exhibited. Hirshfeld surface anal. supports the interactions observed in the crystal structure, and the energy framework anal. provides the stabilization interaction energy among the mol. pairs. The enrichment ratio provides favored contacts between the at. pair and gives strong validation to the halogenhalogen and halogenhydrogen bonds. The DFT studies give more insight into electronic structure and provide a global and local parameter of the mol. NBO studies provide stabilization energy and charge transfer within the mol. The QTAIM studies were used to calculate the strength of the halogen, hydrogen and stacking intermol. interaction. Further, docking studies were carried out for COVID-19 proteins to reveal the structural-function properties of halogen and hydrogen bonds present in the synthesized compound
104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., Product Details of C7H8ClN
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics