The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Name: (4-Chlorophenyl)methanamine.
Li, Shuangqing;Wang, Shuangshuang;Li, Juan;Qi, Yue;Wang, Chao;Zong, Lili;Tan, Choon-Hong research published 《 Monocationic Cinchoninium Catalyzed Asymmetric Oxohydroxylation of Enoates》, the research content is summarized as follows. In this paper, asym. oxohydroxylation of α-alkyl enoates RCH=C(R1)C(O)OR2 (R = Me, cyclohexyl, furan-2-yl, etc.; R1 = Me, prop-2-en-1-yl, prop-2-yn-1-yl, Bn, etc.; RR1 = -(CH2)3-, -(CH2)4-; R2 = Et, Bn, 2-(4-methoxyphenyl)-2-oxoethyl) with potassium permanganate catalyzed by monocationic quaternary ammonium salts I (R3 = H, Bn, (2-bromo-3,5-di-tert-butylphenyl)methyl, [3,5-bis(3,5-di-tert-butylphenyl)phenyl]methyl, etc.; R4 = Br, F, CF3; R5 = F, CF3, [3,5-bis(trifluoromethyl)phenyl]methyl) derived from cinchona alkaloid is reported. A series of α-hydroxy-β-keto esters RC(O)C(R1)(OH)C(O)OR2 were obtained in up to 96% yield and 98% ee under user-friendly conditions. Synthetic application of oxohydroxylation was demonstrated in the synthesis of key chiral building blocks for thapsigargin and camptothecin synthesis. Control experiments indicated that, compared with tetrabutylammonium, monocationic chiral cinchoninium has a dramatic rate acceleration effect on catalytic permanganate oxidation
Name: (4-Chlorophenyl)methanamine, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics