《Visible-light-initiated regioselective sulfonylation/cyclization of 1,6-enynes under photocatalyst- and additive-free conditions》 was written by Meng, Xiao-Xiao; Kang, Qing-Qing; Zhang, Jun-Yao; Li, Qiang; Wei, Wen-Ting; He, Wei-Min. Application In Synthesis of Thiophene-2-sulfonyl chloride And the article was included in Green Chemistry in 2020. The article conveys some information:
Without employing any photocatalyst and additive, an economical, eco-friendly and practical strategy was developed for the visible-light-initiated regioselective sulfonylation/cyclization of 1,6-enynes in a biomass-derived green solvent 2-methylTHF from easily accessible sulfonyl chlorides under open-air conditions at room temperature Compared with conventional heating conditions, the use of a 3 W blue light-emitting diode (LED) or sunlight not only reduces energy consumption but also minimizes side reactions. This transformation showed excellent regioselectivity, mild reaction conditions, broad substrate scope and ease of scale-up. Moreover, mechanistic studies indicated that a sulfonyl radical pathway was involved in this reaction. In the experiment, the researchers used Thiophene-2-sulfonyl chloride(cas: 16629-19-9Application In Synthesis of Thiophene-2-sulfonyl chloride)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Application In Synthesis of Thiophene-2-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics