《Asymmetric Transfer Hydrogenation of Unhindered and Non-Electron-Rich 1-Aryl Dihydroisoquinolines with High Enantioselectivity》 was written by Barrios-Rivera, Jonathan; Xu, Yingjian; Wills, Martin. COA of Formula: C7H6Cl2 And the article was included in Organic Letters on August 21 ,2020. The article conveys some information:
The use of arene/Ru/TsDPEN catalysts bearing a heterocyclic group on the TsDPEN in the asym. transfer hydrogenation (ATH) of dihydroisoquinolines (DHIQs) containing meta- or para-substituted aromatic groups at the 1-position results in the formation of products of high enantiomeric excess. Previously, only 1-(ortho-substituted)aryl DHIQs, or with an electron-rich fused ring gave products with high enantioselectivity; therefore, this approach solves a long-standing challenge for imine ATH. In the experiment, the researchers used many compounds, for example, 3-Chlorobenzylchloride(cas: 620-20-2COA of Formula: C7H6Cl2)
3-Chlorobenzylchloride(cas: 620-20-2) has been used in the reaction of 3-methoxybenzyl chloride and ethyl 4-bromobenzoate in pure water, using zinc dust and a Pd catalyst.COA of Formula: C7H6Cl2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics