《Cu-Catalyzed Direct C7 Sulfonylation of Indolines with Arylsulfonyl Chlorides》 was published in Journal of Organic Chemistry in 2020. These research results belong to Zhi, Changlei; Wang, Qiuling; Liu, Shuang; Xue, Yuting; Shi, Linlin; Zhu, Xinju; Hao, Xin-Qi; Song, Mao-Ping. Product Details of 16629-19-9 The article mentions the following:
An efficient Cu-catalyzed direct sulfonylation of indolines with easily accessible sulfonyl chlorides has been realized under an air atm. via a chelation-assisted strategy. This protocol exhibits several unique characteristics, including broad substrate scope, good functional group tolerance, and operational convenience, which enable a regioselective access to a variety of C-7 functionalized indoline scaffolds in moderate to good yields. The mechanistic study reveals that the sulfonyl radical might be involved in this transformation. The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Product Details of 16629-19-9)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Product Details of 16629-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics