Cellnik, Torsten; Healy, Alan R. published an article in 2022. The article was titled 《Sulfonyl Chlorides as Thiol Surrogates for Carbon-Sulfur Bond Formation: One-Pot Synthesis of Thioethers and Thioesters》, and you may find the article in Journal of Organic Chemistry.Safety of 4-Chlorobenzenesulfonyl chloride The information in the text is summarized as follows:
A method to synthesize thioethers and thioesters directly from readily available sulfonyl chlorides was reported. A transient intermediate formed during phosphine-mediated deoxygenation of sulfonyl chlorides was trapped in situ by activated alcs. or carboxylic acids to effect carbon-sulfur bond formation. The method is operationally simple and tolerates a broad range of functional groups. Special attention was focused on the late-stage diversification of densely functionalized natural products and pharmaceuticals. The experimental part of the paper was very detailed, including the reaction process of 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Safety of 4-Chlorobenzenesulfonyl chloride)
4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Safety of 4-Chlorobenzenesulfonyl chloride Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics