《Hydrolysis of dihydroisoquinoline derivatives activated by sulfonyl or acyl chloride》 was published in Canadian Journal of Chemistry in 2020. These research results belong to Liu, Jianchen; Dang, Xinxin; Chen, Dan; Zhang, Xinyuan; Yang, Zhonglie; Lin, Li; Jiang, Hezhong; Li, Jiahong. Recommanded Product: 16629-19-9 The article mentions the following:
A new, efficient and mild strategy for hydrolysis of 3,4-dihydroisoquinoline imines activated by sulfonyl chloride or acyl chloride was developed, by which method ketosulfonamides I [R = CF3, Ph, 4-MeC6H4, etc.; R1 = H, 5-F, 4-MeO, 5-MeO, 6-MeO, 4,5-di-MeO; R2 = Ph, 4-Br, 2-NO2, etc.] and ketoamides II [R3 = Me, Ph, 2-furyl, etc.] were synthesized. This process tolerated broad scope with respect to both the sulfonyl chloride and acyl chloride with moderate to excellent yields. This protocol features a broad substrate scope for various kinds of 3,4-dihydroisoquinoline and mild reaction conditions without using strong acidic or basic conditions. These features showed that this user-friendly and simple system could be applied in the future to the synthesis of a broader range of amino benzophenones. The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Recommanded Product: 16629-19-9)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Recommanded Product: 16629-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics