SDS of cas: 16629-19-9In 2021 ,《tert-Butyl Hydroperoxide-Initiated Radical Cyclization of 1-(Allyloxy)-2-(1-Arylvinyl)Benzenes with Sulfinic Acids to Access Sulfonated Benzoxepines》 was published in Advanced Synthesis & Catalysis. The article was written by Zhou, Nengneng; Kuang, Kaimo; Wu, Meixia; Wu, Sixin; Xu, Qiankun; Xia, Ziqin; Zhang, Man. The article contains the following contents:
A tert-Bu hydroperoxide-initiated radical cyclization of 1-(allyloxy)-2-(1-arylvinyl)benzenes I (R = H, F, Cl, Br, t-Bu; R1 = H; R2 = C6H5, 4-BrC6H4, 2-thienyl, etc.; R3 = H, Me; R4 = H, Me, OMe, Br; R5 = H, t-Bu; RR1 = -CH=CHCH=CH-; X = O, NTs) with sulfinic acids R6S(O)OH (R6 = 4-CH3C6H4, 1-naphthyl, 2-thienyl, etc.) for the construction of sulfonated benzoxepines II (R7 = C6H5, 4-BrC6H4, 2-thienyl, etc.; R8 = H, Me) is developed. This reaction involves a radical pathway and offers a straightforward route to the formation of seven-membered ring via sulfonylation/cyclization process. This methodol. features mild reaction conditions, a broad substrate scope and good functional group tolerance. After reading the article, we found that the author used Thiophene-2-sulfonyl chloride(cas: 16629-19-9SDS of cas: 16629-19-9)
Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. SDS of cas: 16629-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics