Verma, Astha; Grams, R. Justin; Rastatter, Brett P.; Santos, Webster L. published the artcile< Semireduction of alkynoic acids via a transition metal-free α borylation-protodeborylation sequence>, Recommanded Product: 3-(4-Chlorophenyl)propiolic acid, the main research area is acrylic acid preparation; alkynoic acid semiredn diastereoselective.
A method for the semi-reduction of alkynoic acids through an α-borylation and subsequent protodeborylation mechanism was developed. The transition metal-free protocol is achieved through the activation of bis(pinacolato)diboron by an in-situ generated carboxylate moiety yielding aryl acrylic acids. Our studies demonstrate an unprecedented dual role for the carboxylate anion that involves the activation of the diboron reagent and a directing effect in the α-borylation.
Tetrahedron published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Recommanded Product: 3-(4-Chlorophenyl)propiolic acid.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics