Month: February 2023

Preparation and ligand displacement reactions of diene(polyfluorophenyl)platinum(II) complexes was written by Deacon, G. B.;Nelson-Reed, K. T.. And the article was included in Journal of Organometallic Chemistry in 1987.HPLC of Formula: 12083-92-0 This article mentions the following:

The complexes PtR₂(diene) [R = C₆F₅ or p-HC₆F₄; diene = cis,cis-cycloocta-1,5-diene (cod), dicyclopentadiene (dcy), norbornadiene (nbd), hexa-1,5-diene (hex)] have been prepared by the organolithium route. Reaction of PtCl₂(cod) with an equimolar amount of TlO₂CR (R = C₆F₅, p-HC₆F₄) in pyridine yields Pt(R)Cl(cod), which have been converted into Pt(R)X(cod) (X = Br or iodo) by halogen exchange reactions. Other decarboxylations result in diene displacement giving cis-Pt(C₆F₅)Cl(py)₂ and cis– and trans-Pt(C₆F₅)₂(py)₂. The complexes, cis-Pt(C₆F₅)₂L₂ (L = py or Ph₃P) and cis-Pt(p-HC₆F₄)₂(PPh₃)₂ are formed by ligand replacement reactions of PtR₂(cod), but Pt(C₆F₅)₂ (cod) does not react with N,N,N‘,N‘-tetramethylethylenediamine (tmed) nor Pt(C₆F₅)₂(nbd or dcy) with ethylenediamine (en). Diene displacement occurs more readily from PtR₂(hex) giving Pt(C₆F₅)₂L₂ [L₂ = cis-(NH₃)₂, en, tmed, 1,10-phenanthroline) and cis-Pt(p-HC₆F₄)₂(PPh₃)₂. In the experiment, the researchers used many compounds, for example, Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) (cas: 12083-92-0HPLC of Formula: 12083-92-0).

Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) (cas: 12083-92-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.HPLC of Formula: 12083-92-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Novel photocycloadditions of electron-deficient nitrones to 2-methyl-2-butene was written by Sehgal, R. K.;Griffin, G. W.. And the article was included in Liebigs Annalen der Chemie in 1991.Category: chlorides-buliding-blocks This article mentions the following:

Irradiation of (E)-PhN(O):CPhR (I; R = CN, CO₂Me) with Me₂C:CHMe gave oxazolidines in which O became attached to the less substituted terminus of the olefin. The oxazolidines from I (R = CO₂Me) could be isolated, but those from I (R = CN) were more labile and underwent ionization to an oxazolinium ion, followed by nucleophilic attack by CN^– and ring opening, to give PhC(:NPh)OCHMeCMe₂CN. Mechanisms were discussed. In the experiment, the researchers used many compounds, for example, Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6Category: chlorides-buliding-blocks).

Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Thermo-responsive graft copolymer PSf-g-PNIPM: Reducing the structure parameter via morphology control of forward osmosis membrane substrates was written by Salehi, Hasan;Shakeri, Alireza;Lammertink, Rob G. H.. And the article was included in Journal of Membrane Science in 2022.Electric Literature of C9H3Cl3O3 This article mentions the following:

An amphiphilic graft copolymer, consisting of a polysulfone (PSf) main chain and poly(n-isopropylacrylamide) (PNIPM) grafts, was synthesized via a combination of atom transfer radical polymerization and click chem. The copolymer’s structure characteristics (PNIPM length and content) substantially impacts membrane morphol. and performance, and were optimized firstly. The resulting copolymer PSf-g-PNIPM with the best characteristics was used as an additive in the fabrication of PSf porous substrates by phase inversion. The effect of the graft copolymer on the physicochem. characteristics and performance of PSf substrate was thoroughly studied. The pure water permeability displays a temperature dependency for PSf substrates with 20% PSf-g-PNIPM, with the maximum above the LCST of the PNIPM side chains. Thin film composite membranes formed on these substrates via interfacial polymerization show a significantly improved water flux during forward osmosis operation. The morphol. and performance of the PSf-g-PNIPM modified substrate can be further tuned by the casting medium temperature Membranes formed below the LCST show higher porosity and water flux. In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1Electric Literature of C9H3Cl3O3).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Electric Literature of C9H3Cl3O3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Delivering strong 1H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange was written by Rayner, Peter J.;Burns, Michael J.;Olaru, Alexandra M.;Norcott, Philip;Fekete, Marianna;Green, Gary G. R.;Highton, Louise A. R.;Mewis, Ryan E.;Duckett, Simon B.. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 2017.Application of 442903-28-8 This article mentions the following:

Hyperpolarization turns typically weak NMR and MRI responses into strong signals so that ordinarily impractical measurements become possible. The potential to revolutionize anal. NMR and clin. diagnosis through this approach reflect this area’s most compelling outcomes. Methods to optimize the low-cost parahydrogen-based approach signal amplification by reversible exchange with studies on a series of biol. relevant nicotinamides and Me nicotinates are detailed. These procedures involve specific ²H labeling in both the agent and catalyst and achieve polarization lifetimes of 鈭? min with 50% polarization in the case of methyl-4,6-d₂-nicotinate. Because a 1.5-T hospital scanner has an effective ¹H polarization level of just 0.0005% this strategy should result in compressed detection times for chem. discerning measurements that probe disease. To demonstrate this technique’s generality, the authors exemplify further studies on a range of pyridazine, pyrimidine, pyrazine, and isonicotinamide analogs that feature as building blocks in biochem. and many disease-treating drugs. In the experiment, the researchers used many compounds, for example, Methyl 2,4-dichloronicotinate (cas: 442903-28-8Application of 442903-28-8).

Methyl 2,4-dichloronicotinate (cas: 442903-28-8) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application of 442903-28-8

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Acyl/aroyl Meldrum’s acid as an enol surrogate for the direct organocatalytic synthesis of 伪,尾-unsaturated ketones was written by Khopade, Tushar M.;Warghude, Prakash K.;Mete, Trimbak B.;Bhat, Ramakrishna G.. And the article was included in Tetrahedron Letters in 2019.Reference of 5344-49-0 This article mentions the following:

The operationally simple, robust and straightforward organocatalytic protocol is developed for the synthesis of E-selective 伪,尾-unsaturated ketones. The method utilizes simple and easily accessible starting materials such as Meldrum’s acid, carboxylic acid, aldehyde and simple bifunctional amine catalyst. The tandem organocatalytic process utilizes acyl/aroyl Meldrum’s acid as an enol surrogate for the effective Doebner-Knoevenagel type condensation reactions. A wide variety of aldehydes, carboxylic acids and base sensitive functional groups are well tolerated under the mild reaction conditions. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-nitrobenzoic acid (cas: 5344-49-0Reference of 5344-49-0).

2-Chloro-6-nitrobenzoic acid (cas: 5344-49-0) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Reference of 5344-49-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and properties of high-temperature mesomorphic polysiloxane (MEPSIL) solvents: biphenyl- and terphenyl-based nematic systems was written by Apfel, M. A.;Finkelmann, H.;Janini, G. M.;Laub, R. J.;Luehmann, B. H.;Price, A.;Roberts, W. L.;Shaw, T. J.;Smith, C. A.. And the article was included in Analytical Chemistry in 1985.Recommanded Product: Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) This article mentions the following:

Mesomorphic (liquid-crystalline) side-chain siloxanes were prepared for evaluation as stationary phases in gas chromatog. by hydrosilylation of 4-(allyloxy)benzoate esters by Me hydrogen siloxanes in the presence of a dicyclopentadienylplatinum (II)chloride聽聽[12083-92-0] catalyst. The products were characterized by IR, NMR, gas chromatog., DSC, elemental anal., and hot-stage, polarized optical microscopy. Their selectivity was substantially different from that of other common gas chromatog. solvents. The one best suited for use in gas chromatog. had m.p. 139掳, nematic-isotropic transition temperature 319掳, and practical operating limits of 150 to >300掳. In the experiment, the researchers used many compounds, for example, Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) (cas: 12083-92-0Recommanded Product: Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II)).

Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II) (cas: 12083-92-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: Dichlorodi(cyclopenta-1,3-dien-1-yl)platinate(II)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A versatile living polymerization method for aromatic amides was written by Pal, Subhajit;Nguyen, Dinh Phuong Trinh;Molliet, Angelique;Alizadeh, Mahshid;Crochet, Aurelien;Ortuso, Roberto D.;Petri-Fink, Alke;Kilbinger, Andreas F. M.. And the article was included in Nature Chemistry in 2021.Computed Properties of C19H15Cl This article mentions the following:

Polycondensation polymers typically follow step-growth kinetics assuming all functional groups are equally likely to react with one another. If the reaction rates with the chain end can be selectively accelerated, living polymers can be obtained. Here we report on two chlorophosphonium iodide reagents that have been synthesized from triphenylphosphine and tri(o-methoxyphenyl)phosphine. The former activates aromatic carboxylic acids as acid chlorides in the presence of secondary aromatic amines and the latter even in the presence of primary aromatic amines. These reagents allow p-aminobenzoic acid derivatives to form solution-stable activated monomers that polymerize in a living fashion in the presence of amine initiators. Other aryl amino acids and even dimers of aryl amino acids can be polymerized in a living fashion when slowly added to the phosphonium salt in the presence of an amine initiator. Diblock copolymers and triblock terpolymers of aryl amino acids can be prepared even in the presence of electrophilic functional groups. In the experiment, the researchers used many compounds, for example, (Chloromethanetriyl)tribenzene (cas: 76-83-5Computed Properties of C19H15Cl).

(Chloromethanetriyl)tribenzene (cas: 76-83-5) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Computed Properties of C19H15Cl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Installation of synergistic binding sites onto porous organic polymers for efficient removal of perfluorooctanoic acid was written by Liu, Xiongli;Zhu, Changjia;Yin, Jun;Li, Jixin;Zhang, Zhiyuan;Li, Jinli;Shui, Feng;You, Zifeng;Shi, Zhan;Li, Baiyan;Bu, Xian-He;Nafady, Ayman;Ma, Shengqian. And the article was included in Nature Communications in 2022.Product Details of 76-83-5 This article mentions the following:

Herein, we report a strategy to construct highly efficient perfluorooctanoic acid (PFOA) adsorbents by installing synergistic electrostatic/hydrophobic sites onto porous organic polymers (POPs). The constructed model material of PAF-1-NDMB (NDMB = N,N-dimethyl-butylamine) demonstrates an exceptionally high PFOA uptake capacity over 2000 mg g^-1, which is 14.8 times enhancement compared with its parent material of PAF-1. And it is 32.0 and 24.1 times higher than benchmark materials of DFB-CDP (尾-cyclodextrin (尾-CD)-based polymer network) and activated carbon under the same conditions. Furthermore, PAF-1-NDMB exhibits the highest k₂ value of 24,000 g mg^-1 h^-1 among all reported PFOA sorbents. And it can remove 99.99% PFOA from 1000 ppb to <70 ppt within 2 min, which is lower than the advisory level of Environmental Protection Agency of United States. This work thus not only provides a generic approach for constructing PFOA adsorbents, but also develops POPs as a platform for PFOA capture. In the experiment, the researchers used many compounds, for example, (Chloromethanetriyl)tribenzene (cas: 76-83-5Product Details of 76-83-5).

(Chloromethanetriyl)tribenzene (cas: 76-83-5) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Product Details of 76-83-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Catalytic enantioselective synthesis of carboxy-substituted 2-isoxazolines by cascade oxa-Michael-cyclization was written by Lee, Hyo-Jun;Eun, Bora;Sung, Eonseon;Hwang, Gil Tae;Ko, Young Kwan;Cho, Chang-Woo. And the article was included in Organic & Biomolecular Chemistry in 2018.Product Details of 697-73-4 This article mentions the following:

An efficient quinidine-based phase-transfer-catalyzed enantioselective cascade oxa-Michael-cyclization reaction of hydroxylamine with various 尾-carboxy-substituted 伪,尾-unsaturated ketones has been achieved for the preparation of chiral carboxy-substituted 2-isoxazolines. This cascade reaction provided the desired products in good yields (up to 98%) with excellent enantioselectivities (91-96% ee). In addition, the cascade reaction was effectively applied to the first catalytic asym. synthesis of the herbicide (S)-methiozolin. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Product Details of 697-73-4).

2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 697-73-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Design, synthesis, and characterization of rhein analogs as novel inhibitors of scavenger receptor A was written by Zheng, Yi;Li, Xia;Pagare, Piyusha P.;Yuan, Yunyun;Wang, Xiang-Yang;Zhang, Yan. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2017.Reference of 90064-48-5 This article mentions the following:

Scavenger receptor A (SRA) has been known as an immunosuppressive factor and therefore therapeutic inhibition of SRA may be potentially exploited for cancer immunotherapy. The previous work suggested that rhein may act as an inhibitor of SRA in reversing immunosuppression of SRA during T cells activation. Herein, three deconstruction analogs of rhein were further studied as inhibitors of SRA. These three compounds, particularly compound I, also known as a natural product danthron, enhanced T cells activation, indicated by increased transcriptional activation of interleukin 2 (Il2) gene, production of IL-2 protein, and proliferation of T cells. Addnl., the interaction between these compounds and SRA was studied by mol. modeling. Compound I showed a favorable binding mode with the cysteine rich domain of SRA protein compared to the other compounds Collectively, those results would provide insight for future design and development of next generation rhein derivatives as SRA inhibitors. In the experiment, the researchers used many compounds, for example, 4-Chloro-2,5-dimethoxybenzaldehyde (cas: 90064-48-5Reference of 90064-48-5).

4-Chloro-2,5-dimethoxybenzaldehyde (cas: 90064-48-5) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Reference of 90064-48-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics