Electrochemical Synthesis of Quinazolinones by the Metal-Free and Acceptor-Free Dehydrogenation of 2-Aminobenzamides was written by Yao, Yan;Meng, Xiu-Jin;Teng, Qing-Hu;Chen, Yan-Yan. And the article was included in Synlett in 2020.Product Details of 620-19-9 This article mentions the following:
An efficient approach has been developed for the construction of quinazolin-4(3H)-ones by the selective anodic dehydrogenative oxidation/cyclization of benzylic chlorides and 2-aminobenzamides [e.g., 2-aminobenzamide + benzyl chloride 鈫?2-phenylquinazolin-4(3H)-one I (80%) employing RVC as anode, Pt as cathode, Bu4NBF4 as electrolyte and MeCN as solvent in undivided cell at constant current of 10mA at 80掳]. The method features acceptor-free and metal-free dehydrogenation of amines to imines; a subsequent intermol. addition provides the products in moderate to good yields. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Product Details of 620-19-9).
1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Product Details of 620-19-9
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics