Synthesis and Characterization of Copper(I)-Cysteine Complex Supported on Magnetic Layered Double Hydroxide as an Efficient and Recyclable Catalyst System for Click Chemistry Using Choline Azide as Reagent and Reaction Medium was written by Pazoki, Farzane;Salamatmanesh, Arefe;Bagheri, Sepideh;Heydari, Akbar. And the article was included in Catalysis Letters in 2020.Formula: C8H9Cl This article mentions the following:
In this study, Fe3O4@LDH@cysteine-Cu(I) nanoparticles (LDH is layered double hydroxides) were designed as a novel and recyclable catalytic system and successfully synthesized. These nanoparticles showed high catalytic activity for preparation of the triazoles I (R1 = H2C:CH, Ph, 4-MeOC6H4, 4-O2NC6H4CO, etc.; R2 = HOCH2, HO2C, Ph, 1-hydroxycyclohexyl, etc.) through reaction of the alkynes R2C顚咰H with organic halides R1CH2X (X = Br, Cl) in the presence of choline azide as reagent and reaction medium. In addition, Fe3O4@LDH@cysteine-Cu(I) could be easily recovered and reused for five times without any significant loss in catalytic activity. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Formula: C8H9Cl).
1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Formula: C8H9Cl
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics