Novel synthesis of isoquinolin-3-ols was written by Ainscough, Martin A.;Temple, Arthur F.. And the article was included in Journal of the Chemical Society, Chemical Communications in 1976.Name: 2-(3-Methoxyphenyl)acetyl chloride This article mentions the following:
Cycloaddition reaction of phenacetyl chlorides with alkyl or aryl thiocyanates in the presence of SnCl4 gave 1-substituted isoquinolin-3-ols. E.g., PhCH2COCl with MeSCN in PhNO2 in the presence of SnCl4 gave 65% 1-methylthioisoquinolin-3-ol (I). In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Name: 2-(3-Methoxyphenyl)acetyl chloride).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Name: 2-(3-Methoxyphenyl)acetyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics