Oxidation of triethylene glycol by N-chlorosaccharin in cetyltrimethylammonium bromide catalyzed system: a kinetics and mechanistic study was written by Sharma, Vandana;Sharma, K. V.;Bhagwat, V. W.. And the article was included in Physical Chemistry: An Indian Journal in 2008.Quality Control of 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide This article mentions the following:
The kinetics and mechanistic study of cetyltrimethylammonium bromide catalyzed oxidation of triethylene glycol [2,2′-ethylene dioxybis(ethanol)] by N-chlorosaccharin in aqueous acetic acid medium in presence of perchloric acid were studied at 303-323K temperature range. The reaction has first order dependence on N-chlorosaccharin concentration The reaction rate follows first order kinetics with respect to [triethylene glycol] with excess concentration of other reactants. The micelle effect due to cetyltrimethylammonium bromide- a cationic surfactant was studied. The change in ionic strength shows negligible salt effect. The dielec. effect is pos. Addition of one of (saccharin) retards the reaction rate. Activation parameters are calculated from the Arrhenius plot. A suitable mechanism was proposed in consistence with the kinetic data. In the experiment, the researchers used many compounds, for example, 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0Quality Control of 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide).
2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Quality Control of 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics