Scandium triflate-catalyzed transesterification of carboxylic esters was written by Remme, Nicole;Koschek, Katharina;Schneider, Christoph. And the article was included in Synlett in 2007.Safety of Methyl 2-chloro-2-phenylacetate This article mentions the following:
The direct transesterification of carboxylic esters is efficiently catalyzed with Sc(OTf)3 (10 mol%) in boiling alc. solvent. Me, Et, iso-Pr, and allyl esters were prepared from a broad range of different substrates in high yields. The application of microwave irradiation led to significantly reduced reaction times. In the experiment, the researchers used many compounds, for example, Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6Safety of Methyl 2-chloro-2-phenylacetate).
Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Safety of Methyl 2-chloro-2-phenylacetate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics