Singh, Meenakshi et al. published their research in RSC Advances in 2014 | CAS: 3438-16-2

5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Synthetic Route of C8H7ClO3

Design, synthesis and mode of action of some benzothiazole derivatives bearing an amide moiety as antibacterial agents was written by Singh, Meenakshi;Singh, Sudhir K.;Gangwar, Mayank;Nath, Gopal;Singh, Sushil K.. And the article was included in RSC Advances in 2014.Synthetic Route of C8H7ClO3 This article mentions the following:

In this study ten benzothiazole derivatives bearing the amide moiety were designed, synthesized and evaluated for their antibacterial activity and possible mode of action. Structures of the synthesized compounds were elucidated by spectral data. Four different Gram-neg. and two different Gram-pos. bacterial strains were used in antibacterial activity tests. Among all the synthesized compounds, compound A07 displayed the most potent inhibitory activity with min. inhibitory concentration (MIC) values of 15.6, 7.81, 15.6, 3.91 μg ml-1 against S. aureus, E. coli, S. typhi and K. pneumoniae resp. Structure-activity relationship (SAR) studies revealed that electronic and lipophillic factors of the Ph ring had a significant effect on the antimicrobial activity of the designed compounds The benzothiazole bearing amide (A01-A10) series exhibited different modes of action based on aryl group substitution as revealed by studies on intact bacterial cells and plasmid DNA. The present study provides us two active compounds (A07 and A10) with a membrane perturbing mode of action, and an intracellular mode of action due to binding with DNA along with potent activity against clin. relevant pathogens E. coli and S. aureus. In the experiment, the researchers used many compounds, for example, 5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2Synthetic Route of C8H7ClO3).

5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Synthetic Route of C8H7ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics