Polymer amino-protecting groups based on tert-butoxycarbonyl- and benzoylcarbonyl function-containing polymethacrylamides was written by Rehse, Henning;Ritter, Helmut. And the article was included in Makromolekulare Chemie in 1989.Related Products of 18437-66-6 This article mentions the following:
The synthesis of tert-butoxycarbonyl- and benzyloxycarbonyl-modified monomers was performed by the addition of p-ClC6H4NCO or PhCH2NCO to the free OH groups of N-(2-hydroxy-2-methylpropyl)methacrylamide, N-(2-hydroxy-2-methylpropyl)-6-methylacrylamidohexanamide and N-β-hydroxyphenethylmethacrylamide. The monomers were homopolymerized and copolymerized with Me methacrylate. The kinetics of acidic-induced amine cleavage from the amino-protecting groups was followed by NMR spectroscopy, and the polymers were suitable amino-protecting groups. Ca2+ ions enhanced the rate of amine cleavage considerably. Neighboring group effects and the influence of comonomers and spacer groups on the reactivity of the urethane groups were also discussed. In the experiment, the researchers used many compounds, for example, tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6Related Products of 18437-66-6).
tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Related Products of 18437-66-6
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics