A mild and green method for the N-BOC protection of amines without assistant of catalyst under solvent-free conditions was written by Mojtahedi, Mohammad Majid;Niknejad, Nina;Veisi, Hojat. And the article was included in Letters in Organic Chemistry in 2013.Reference of 18437-66-6 This article mentions the following:
A facile, green and versatile method for the Boc protection of amines has been developed by a treatment with (Boc)2O without any additive at room temperature The method is general for the preparation of N-Boc derivatives of aliphatic (acyclic and cyclic), aromatic, and heteroaromatic amines; primary and secondary amines. The advantages of this method are green, simplicity, short reaction times and excellent yields. In the experiment, the researchers used many compounds, for example, tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6Reference of 18437-66-6).
tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Reference of 18437-66-6
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics