Synthesis and fungicidal activity of phenazine-1-carboxylic triazole derivatives was written by Li, Xu-Jun;Zhang, Wei;Zhao, Chi-Na;Wu, Qing-Lai;Li, Jun-Kai;Xu, Zhi-Hong. And the article was included in Journal of Asian Natural Products Research in 2021.Recommanded Product: 1-(Chloromethyl)-3-methylbenzene This article mentions the following:
A total of 15 novel-substituted 3-(benzylsulfanyl)-1H-1,2,4-triazol-5-ylamines I [R = 3-MeC6H4, 2-FC6H4, 2,4-Cl2C6H3, etc.] and 10 novel-substituted 3-benzylmercapto-1,2,4-triazole derivatives II were synthesized based on the natural product phenazine-1-carboxylic acid (PCA). Their structures were confirmed by 1H-NMR, 13C-NMR, HRMS and X-ray. Most substituted 3-benzylmercapto-1,2,4-triazole derivatives II displayed very strong fungicidal activity against one or multiple plant pathogens in vitro and in vivo. Compounds II [R = 4-MeC6H4, 4-iPrC6H4, 4-tBuC6H4, etc.] showed a broad spectrum of fungicidal activity. Further field experiments indicated that compounds II [R = 4-MeC6H4, 2-FC6H4, 4-iPrC6H4, etc.] displayed better efficacy against rice blast (Pyricularia oryzae) than PCA. These data demonstrated that compounds II [R = 4-MeC6H4, 2-FC6H4, 4-iPrC6H4, etc.] were promising fungicidal candidates, deserving further studies. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Recommanded Product: 1-(Chloromethyl)-3-methylbenzene).
1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: 1-(Chloromethyl)-3-methylbenzene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics