Iodine-mediated neutral and selective N-Boc deprotection was written by Kumar, G. Pavan;Rambabu, D.;Rao, M. V. Basaveswara;Pal, Manojit. And the article was included in Journal of Chemistry in 2013.Reference of 18437-66-6 This article mentions the following:
A simple, efficient, and alternative method was developed for the N-Boc deprotection of structurally diverse protected amines. Selective removal of N-Boc groups was achieved with excellent yields under solvent-free conditions or in a solvent using I2 as a catalyst. The methodol. involving the use of iodine for N-Boc deprotection of protected amines represents an effective and useful alternative to previously reported methods. In the experiment, the researchers used many compounds, for example, tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6Reference of 18437-66-6).
tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Reference of 18437-66-6
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics