Diaza-18-crown-6 ethers containing partially-fluorinated benzyl sidearms: Effects of covalently bonded fluorine on the alkali metal complexation was written by Chi, Ki-Whan;Shim, Kwang Taeg;Huh, Hwang;Lee, Uk;Park, Young Ja. And the article was included in Bulletin of the Korean Chemical Society in 2005.Name: 2-(Chloromethyl)-1,3-difluorobenzene This article mentions the following:
The stability constants for the diaza-18-crown-6 ethers (2-6) and alkali metal cations (Na+, K+, Rb+ and Cs+) were determined using potentiometry in 95% methanol. For each metal ion the stability constants of the partially-fluorinated ligands 3-6 were larger than that of the non-fluorinated ligand 2, which might reflect an interaction between fluorine atoms and alkali metal cations. The stability constant of the ligand 4 was larger than that of the ligand 5 for each metal cation tested. This finding was also supported by the results of cation-induced chem. shifts in 1H-, 19F-NMR and extraction experiment The potentiometry and NMR results as well as the X-ray crystal structures revealed that the position and number of fluorine atoms in the benzyl side arms was crucial for the enhanced interaction between a ligand and an alkali metal. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Name: 2-(Chloromethyl)-1,3-difluorobenzene).
2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Name: 2-(Chloromethyl)-1,3-difluorobenzene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics