Synthetic and pharmacological evaluation of some pyridine containing thiazolidinones was written by Firke, S. D.;Firake, B. M.;Chaudhari, R. Y.;Patil, V. R.. And the article was included in Asian Journal of Research in Chemistry in 2009.Computed Properties of C7H3Cl2NS This article mentions the following:
Several of 2-(2-pyridinyloxy)acetic acid 2-(4-oxo-2-thiazolidinylidene)hydrazide derivatives were obtained by a cyclization reaction of isothiocyanates with 2-(2-pyridinyloxy)acetic acid 2-[(amino)thioxomethyl]hydrazide (thiosemicarbazide) derivatives with chloroacetic acid. The product structures were confirmed by their anal. and spectral data. All the above-mentioned target compounds were evaluated for their activity as antidiabetic agents using a GOD-POD method on Wistar strain rats. The acute toxicity (LD50) values of these compounds were also reported. here. The test compounds showed significant antidiabetic activity. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Computed Properties of C7H3Cl2NS).
2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Computed Properties of C7H3Cl2NS
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics