Month: January 2023

Nickel-catalyzed reductive benzylation of tertiary alkyl halides with benzyl chlorides and chloroformates was written by Wang, Jiabao;Gong, Yuxin;Sun, Deli;Gong, Hegui. And the article was included in Organic Chemistry Frontiers in 2021.Computed Properties of C8H9Cl This article mentions the following:

Ni-Catalyzed reductive cross-coupling of tertiary alkyl halides with benzyl chlorides and chloroformates has been developed, which provides an efficient method for the construction of benzylated all-carbon quaternary centers in moderate to excellent yields with high functional group tolerance. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Computed Properties of C8H9Cl).

1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Computed Properties of C8H9Cl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Monoamine-modified thin film composite nanofiltration membrane for permselective separation of fermentation bioproducts was written by Gonzales, Ralph Rolly;Shintani, Takuji;Sunami, Shunsuke;Sasaki, Yuji;Nakagawa, Keizo;Yoshioka, Tomohisa;Matsuyama, Hideto. And the article was included in Journal of Applied Polymer Science in 2022.Application In Synthesis of Trimesoylchloride This article mentions the following:

One process involved in biorefinery for generation of value-added products is fermentation After fermentation, the downstream bioproduct purification process is conventionally performed by organic solvent extraction, which is environmentally-hazardous and costly. Membrane-based separation is a cost-efficient and environmentally-benign method for bioproduct separation and purification In this study, a thin film composite (TFC) nanofiltration (NF) membrane was prepared and the pore size and charge of the polyamide layer were controlled by introducing iminodiacetic acid (IDA), a charged monoamine monomer, with piperazine (PIP) during interfacial polymerization (IP). The newly-developed NF membrane was found to have a mol. weight cut-off (MWCO) of 500 to 1350 Da, allowing the permeation of the fermentation product, while rejecting other higher mol. weight compounds IDA addition in the aqueous amine solution during IP effectively engineered the MWCO values and pore sizes of TFC NF membranes for specific applications, such as separation of fermentation bioproducts. This study successfully showed that IDA reduced the diffusivity of PIP during IP, which neg. affected the polyamide formation and membrane performance. The optimal PIP:IDA concentration ratio was determined by MWCO and effective pore diameter for effective bioproduct separation and purification, which could not be performed by the current com.-available NF membranes. In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1Application In Synthesis of Trimesoylchloride).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Application In Synthesis of Trimesoylchloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Effectiveness of sodium sulfite as an electron acceptor for bioenhanced treatment of salt-containing water produced from ASP flooding was written by Zhang, Xinxin;Wei, Dong;Li, Chunying;Wei, Li;Zhao, Min. And the article was included in Chemosphere in 2021.Formula: C18H37Cl This article mentions the following:

The wastewater produced from alk.-surfactant-polymer (ASP) flooding is a complex multiphase mixture that contains oil, polymers, surfactants and other pollutants and is thus a salt-containing industrial waste recalcitrant to treatments. Through laboratory tests, this study assessed the effectiveness of using sodium sulfite as an electron acceptor for a modified anaerobic baffled reactor (ABR) for removing oil, suspended solids, polymers and surfactants from salt-containing wastewater produced from ASP flooding. During the 90-day operation, the method established in this study successively removed 52.8%, 98.6%, 77.0%, 21.2% and 21.5% of the COD (COD), oil, suspended solids, polymers and surfactants, resp., from the wastewater. The changes in organic compounds in the reactor during the treatment were monitored through gas chromatog.-mass spectrometry (GC-MS), and the results showed that the established method was very effective in removing alkanes, alkenes, cycloalkanes, aromatic hydrocarbons and esters, and the organic macromols. in the wastewater were degraded to small mols. The main bacterial species and microbial communities in the reactor were characterized using mol. biol. techniques, and the results indicated that under the stress of high pH and salts, Halomonas sp. gradually dominated and played a major role in degrading hydrocarbons. The findings of this study can aid the development of a cost-effective biol. system to treat the water produced from ASP flooding. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Formula: C18H37Cl).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Formula: C18H37Cl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A scalable method to fabricate high-performance biomimetic membranes for seawater desalination: Incorporating pillar[5]arene water nanochannels into the polyamide selective layer was written by Lim, Yu Jie;Lai, Gwo Sung;Zhao, Yali;Ma, Yunqiao;Torres, Jaume;Wang, Rong. And the article was included in Journal of Membrane Science in 2022.COA of Formula: C9H3Cl3O3 This article mentions the following:

In this work, we explored the practicability of a nanochannel-based biomimetic membrane (NBM) incorporating pillar[5]arene water channels for seawater reverse osmosis (SWRO) desalination. Two classes of peptide-attached biomimetic channels, (pR)-pillar[5]arenes (pRPH) and (pS)-pillar[5]arenes (pSPH) were integrated into the selective layer of SWRO membranes via interfacial polymerization on the top side of a polysulfone (PSf) support membrane. Here, pSPH is a non-identical stereoisomer of pRPH and was used as a neg. control to pRPH to elucidate the flux enhancement effect contributed by pRPH. The optimized NBM presented a water permeability of 2.52 L m^-2 h^-1 bar^-1 and 99.5% rejection under SWRO testing conditions of 50 bar applied pressure and 32,000 mg/L NaCl as feed solution The 62% permeability increment with reference to the control membrane is hypothesized to originate from hybrid polyamide layers that were rougher with more voids (higher effective surface area and lower hydraulic resistance for water transport) as well as the conceivable water transport pathways provided by the pRPH channels. The simulation results from module-scale modeling suggest that the optimized NBM could lead to 7.2% savings in specific energy consumption of the membrane unit stage (or reduce the required membrane area by 25%) with respect to the com. SWC4-LD membrane. The performance of the optimized NBM was further assessed in a one-week desalination test using an actual seawater feed gathered from an SWRO plant in Singapore. The robust NBM exhibited stable performance and �8% higher water flux (42 L m^-2 h^-1) than SWC4-LD with a comparable rejection of 99.3%, suggesting the feasibility of pillar[5]arene-based biomimetic membranes for seawater desalination. In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1COA of Formula: C9H3Cl3O3).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C9H3Cl3O3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Manganese-Catalyzed ortho-C-H Amidation of Weakly Coordinating Aromatic Ketones was written by Kong, Xianqiang;Xu, Bo. And the article was included in Organic Letters in 2018.Product Details of 777-44-6 This article mentions the following:

An efficient manganese-catalyzed ortho-C-H amidation of weakly coordinating aromatic ketones using the readily available sulfonyl azide as the amination reagent is developed. The key step is the ketone directed aromatic metalation using the in situ generated reactive Mn intermediate, MnMe(CO)₅. This method offers excellent chem. yields, high regioselectivities, and good functional group tolerance. In the experiment, the researchers used many compounds, for example, 3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6Product Details of 777-44-6).

3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Product Details of 777-44-6

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Evaluation of the flavor compounds of Pleurotus eryngii as affected by baking temperatures using HS-SPME-GC-MS and electronic nose was written by Zhu, Mengwei;Hu, Zhizhong;Liang, Miao;Song, Lingyong;Wu, Wentao;Li, Ruili;Li, Zhihua;Zhang, Junsong. And the article was included in Journal of Food Processing and Preservation.Electric Literature of C10H19ClO2 This article mentions the following:

This study evaluated the effect of different baking temperatures on the flavor compounds of Pleurotus eryngii using electronic nose (E-nose) and headspace solid-phase microextraction gas chromatog.-mass spectrometry (HS-SPME-GC-MS). A total of 105 volatile compounds were detected, including aldehydes (14), esters (18), alcs. (23), ketones (7), acids (6), pyrazines (8), hydrocarbons (18), and other compounds (11). The results of E-nose combined with the content of volatile compounds indicated that with the increase of baking temperatures, the content of alcs. and esters decreased while the content of aldehydes, ketones, and pyrazines increased, which increased the malty, sweet, and roasted nutty flavor. In addition, 11 volatile compounds were identified as key odor compounds with relative odor activity value (ROAV) > 1. P. eryngii samples baked at 120°C possessed the most varieties of volatile compounds (up to 69), which increased the richness and layering of flavor of baked P. eryngii as reflected by sensory anal. These results may provide guidance for the controllable formation of flavor compounds in P. eryngii by using baking method. Novelty impact statement : The sensory anal. showed that the sample Pleurotus eryngii baked at 120°C increased the richness and layering of flavor of baked P. eryngii, which was basically in accordance with the component anal. results. Therefore, The results obtained in this study could provide guidance for controlling the formation of odor and taste of P. eryngii by using baking method. In the experiment, the researchers used many compounds, for example, Chloroformicacidn-nonylester (cas: 57045-82-6Electric Literature of C10H19ClO2).

Chloroformicacidn-nonylester (cas: 57045-82-6) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Electric Literature of C10H19ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The challenge of micropollutants in surface water of the Yangtze River was written by Yang, Yinjie;Chen, Zhongli;Zhang, Jialing;Wu, Siqi;Yang, Li;Chen, Lin;Shao, Ying. And the article was included in Science of the Total Environment in 2021.Reference of 101-20-2 This article mentions the following:

The Yangtze River, the third largest river and supporting nearly one-third of Chinese population, has been severely polluted in recent decades. Among the numerous pollutants, organic micropollutants, as one kind of important emerging contaminants, are currently key contaminants of concern. However, few studies have focused on their mixture environmental impacts, especially for the complex environmental mixtures In the current study, four categories of organic micropollutants, including 16 polycyclic aromatic hydrocarbons (PAHs), 32 polychlorinated biphenyls (PCBs), 27 organochlorine pesticides (OCPs) and 20 pharmaceutical and personal care products (PPCPs) are analyzed in 10 study sites on the Yangtze River. Subsequently, comprehensive risk assessment for micropollutant mixtures was conducted by risk quotient based on the sum of PEC/PNEC values (RQ_MEC/PNEC) and risk quotient based on the toxic units (RQ_STU). The mixture risk evaluation based on the detected environmental concentrations indicates that micropollutant mixtures in surface water of the Yangtze River exhibited relative high risks for aquatic organisms. The observed results revealed that mixture risk assessments have to consider the complexity of environmental samples; PCBs dominated main mixture risks in the upper stream; PAHs contributed major comprehensive risks in the middle stream; and OCPs were the key micropollutants in the downstream. The outcomes of the present study here can serve for pollution control in the Yangtze River, which provide the scientific underpinnings and regulatory reference for risk management and river protection. In the experiment, the researchers used many compounds, for example, 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea (cas: 101-20-2Reference of 101-20-2).

1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea (cas: 101-20-2) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Reference of 101-20-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Alkylation of enaminoketone with a modified carane skeleton. Formation of stable β-diketone monoimines was written by Tkachev, A. V.;Popov, S. A.. And the article was included in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) in 1997.COA of Formula: C7H5ClF2 This article mentions the following:

Alkylation of a bicyclic enaminoketone, 1-[(1R,5R)-3-amino-6,6-dimethylbicyclo[3.1.0]hex-2-en-2-yl]ethanone, with highly reactive alkyl halides (Me iodide, benzyl halides, and allyl halides) in a two-phase system benzene-40% aqueous NaOH in the presence of benzyltriethylammonium chloride (BTEA) as phase-transfer catalyst results in formation of stable β-diketone monoimines, derivatives of the series of 1-[(1R,5R)-2-alkyl-3-imino-6,6-dimethylbicyclo[3.1.0]hex-2-yl]ethanone, in 53-81% yields. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4COA of Formula: C7H5ClF2).

2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.COA of Formula: C7H5ClF2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Electrochemically generated N-iodoaminium species as key intermediates for selective methyl sulphonylimination of tertiary amines was written by Huang, Binbin;Yang, Chao;Zhou, Jia;Xia, Wujiong. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Application In Synthesis of 2,4-Dimethoxybenzene-1-sulfonyl chloride This article mentions the following:

A straightforward protocol for approaching N-sulfonylamidines (E/Z)-RS(O)₂N=CHN(R¹)(R²) (R = Me, 2-fluorophenyl, thiophen-2-yl, etc.; R¹ = Me; R² = Et, cyclohexyl, benzyl, etc.; R¹R² = -(CH₂)₅-, -(CH₂)₂O(CH₂)₂-) and I via an electricity-driven, iodine-mediated cross dehydrogenative condensation (CDC) between sulfonamides RS(O)₂NH₂ and tertiary amines CH₃N(R¹)(R²), which features exclusive N-CH₃ selectivity for the amine partners was reported. Mechanistic studies indicate that an in situ generated N-iodoaminium species serves as the key intermediate. In the experiment, the researchers used many compounds, for example, 2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2Application In Synthesis of 2,4-Dimethoxybenzene-1-sulfonyl chloride).

2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Application In Synthesis of 2,4-Dimethoxybenzene-1-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of 3-[p-(pyrazolyl)]phenylsydnones was written by Havanur, Shambhuling B.;Badami, Bharati V.;Puranik, Gurubasav S.. And the article was included in Journal of Heterocyclic Chemistry in 1980.Category: chlorides-buliding-blocks This article mentions the following:

Condensation of p-RC₆H₄NH₂ (R = 1-pyrazolyl, 3,5-dimethyl-1-pyrazolyl, 3,4,5-trimethyl-1-pyrazolyl) with R¹ClCHCO₂Me (R¹ = H, Me, Ph) gave 70-5% p-RC₆H₄NHCHR¹CO₂H which on treatment with NaNO₂ gave 75-80% p-RC₆H₄N(NO)CHR¹CO₂H. Cyclizing the last with Ac₂O gave 60-76% title compounds I. In the experiment, the researchers used many compounds, for example, Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6Category: chlorides-buliding-blocks).

Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics