Reinvestigation of chlorination of saccharin. A mild and convenient synthesis of o-cyanophenylsulfonyl chloride was written by Yoon, Yong Jin;Kang, Yoon Se. And the article was included in Bulletin of the Korean Chemical Society in 1985.Formula: C7H4ClNO3S This article mentions the following:
Treating saccharin with PCl5-ZnCl2 15-30 min at 65-70° gave 85-90 % o-NCC6H4SO2Cl. Refluxing saccharin or its Na salt with POCl3 2-3 h gave 75% N-chlorosaccharin I. In the experiment, the researchers used many compounds, for example, 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0Formula: C7H4ClNO3S).
2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Formula: C7H4ClNO3S
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics