αvβ3 antagonists based on a central benzoic acid scaffold was written by Will, D. W.;Breipohl, G.;Gourvest, J.-F.;Ruxer, J.-M.;Doucet, B.;Auberval, M.;Baron, R.;Gaillard, M.;Gadek, T. R.;Knolle, J.;Stilz, H. U.;Peyman, A.. And the article was included in Polish Journal of Chemistry in 2005.Recommanded Product: 4-Butoxybenzene-1-sulfonyl chloride This article mentions the following:
A series of highly potent αvβ3 antagonists, e.g., I, based on a benzoic acid scaffold and containing an acylguanidine as an Arg-mimetic and sulfonamide side chains is described. The compounds were selective against the fibrinogen receptor αIIbβ3 and they were capable of inhibiting bone resorption in vivo in a TPTX model of osteoporosis. Therefore the compounds were promising drug substances for the treatment of osteoporosis. In the experiment, the researchers used many compounds, for example, 4-Butoxybenzene-1-sulfonyl chloride (cas: 1138-56-3Recommanded Product: 4-Butoxybenzene-1-sulfonyl chloride).
4-Butoxybenzene-1-sulfonyl chloride (cas: 1138-56-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Recommanded Product: 4-Butoxybenzene-1-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics