The design and synthesis of purine inhibitors of CDK2. III was written by Shum, P. W.;Peet, N. P.;Weintraub, P. M.;Le, T. B.;Zhao, Z.;Barbone, F.;Cashman, B.;Tsay, J.;Dwyer, S.;Loos, P. C.;Powers, E. A.;Kropp, K.;Wright, P. S.;Bitonti, A.;Dumont, J.;Borcherding, D. R.. And the article was included in Nucleosides, Nucleotides & Nucleic Acids in 2001.Related Products of 697-73-4 This article mentions the following:
Cyclin-dependent kinases (CDKs) belong to a class of enzymes that control the ability of a cell to enter into and proceed through the cell division cycle. Using purine as a scaffold, we have synthesized a number of nanomolar inhibitors of CDK-2/cyclin E. In this report, the synthesis of a series of piperidine-substituted purine analogs will be presented, as well as some of their in vitro and in vivo biol. effects. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Related Products of 697-73-4).
2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Related Products of 697-73-4
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics