Conventional and non-conventional synthesis of some novel benzofuran incorporated thiadiazoles and triazoles was written by Kundlikar, S. G.;Randhavane, P. V.;Akolkar, H. N.;Karale, B. K.. And the article was included in Indian Journal of Heterocyclic Chemistry in 2016.Safety of 2,4-Dichlorophenylisothiocyanate This article mentions the following:
7-Bromo-5-chlorobenzofuran-2-carbohydrazide on reaction with substituted arylisothiocyanates gave corresponding thiosemicarbazides, further reaction in the presence of acidic and basic medium gave corresponding thiadiazoles and triazoles resp. The structures of all the synthesized compounds were characterized with the help of spectral techniques. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Safety of 2,4-Dichlorophenylisothiocyanate).
2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Safety of 2,4-Dichlorophenylisothiocyanate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics