TBHP/R4N+X– promoted hydroaroylation of dialkyl azodicarboxylates with methyl arenes, aldehydes, aryl methanols and arylmethyl chlorides was written by Adib, Mehdi;Pashazadeh, Rahim;Rajai-Daryasarei, Saideh;Moradkhani, Fatemeh;Jahani, Mehdi;Gohari, Seyed Jamal Addin. And the article was included in Tetrahedron in 2018.Category: chlorides-buliding-blocks This article mentions the following:
Efficient TBHP/R4N+X– promoted hydroaroylations of dialkyl azo-1,2-dicarboxylates with Me arenes, aldehydes, aryl methanols and arylmethyl chlorides were described. These oxidation/oxygenation and hydroaroylation processes were carried out by tert-Bu hydroperoxide as terminal oxidant/oxygen source, and were catalyzed by tetrabutylammonium bromide and tricaprylmethylammonium chloride as the driving force. During this investigation, all these hydroaroylating sources were found to be highly efficient reagents without the need of any transition-metal. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Category: chlorides-buliding-blocks).
1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Category: chlorides-buliding-blocks
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics