Palladium-Catalyzed Synthesis of Tricyclic Indoles via a N-S Bond Cleavage Strategy was written by Zhang, Bo-Sheng;Wang, Fan;Gou, Xue-Ya;Yang, Ying-Hui;Jia, Wan-Yuan;Liang, Yong-Min;Wang, Xi-Cun;Li, Yuke;Quan, Zheng-Jun. And the article was included in Organic Letters in 2021.Quality Control of 2,4-Dimethoxybenzene-1-sulfonyl chloride This article mentions the following:
In palladium/norbornene (Pd/NBE) chem., the “ortho effect” has been proven to be a key factor in the process of β-carbon elimination to extrude NBE. Herein, it is found that the o-iodoaniline protected by a p-methoxybenzenesulfonyl group can recover the “ortho effect” and then undergo N-S bond cleavage with vinyl palladium, thus achieving a highly selective C-N coupling reaction in the Catallani-Lautens reaction system. On the basis of this discovery, a one-step synthesis of highly functionalized tricyclic indole derivatives was realized. In the experiment, the researchers used many compounds, for example, 2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2Quality Control of 2,4-Dimethoxybenzene-1-sulfonyl chloride).
2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Quality Control of 2,4-Dimethoxybenzene-1-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics