Synthesis of (E)-α-chloromethyl vinyl sulfones by 1, 2-radical difunctionalization of allenes with sodium sulfinates and iron(III) chloride hexahydrate was written by Wu, Zhuoxiong;Yu, Hui. And the article was included in Tetrahedron Letters in 2022.Recommanded Product: 3-(Trifluoromethyl)benzene-1-sulfonyl chloride This article mentions the following:
An efficient radical chlorosulfonylation of allenes was disclosed and vinylsulfones were prepared smoothly under mild conditions. By using sodium sulfinates as radical precursors, iron(III) chloride hexahydrate (FeCl3.6H2O) as oxidant and chloride source, allenes were converted into (E)-α-chloromethyl vinylsulfones I [R = Me, Ph, 4-FC6H4, etc., R1 = Ph, R2 = H, X = Cl, Br; R = Ph, R1 = 2-MeC6H4, 4-FC6H4, 4-ClC6H4, etc., R2 = H, Me, X = Cl] via regioselective 1,2-radical difunctionalization process in moderate to good yields. In the experiment, the researchers used many compounds, for example, 3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6Recommanded Product: 3-(Trifluoromethyl)benzene-1-sulfonyl chloride).
3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Recommanded Product: 3-(Trifluoromethyl)benzene-1-sulfonyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics