Synthesis and anticonvulsant activity of 1-substituted benzyl N-substituted 1,2,3-triazole-4-carboxanilides was written by Wang, Junmin;Jun, Changsoo;Chai, Kyuyun;Kwak, Kyungchell;Quan, Zheshan. And the article was included in Progress in Natural Science in 2006.Synthetic Route of C7H5ClF2 This article mentions the following:
Title compounds I [R = (un)substituted phenyl; R1 = H, Me, Pr] were prepared by heterocyclization of benzyl azides with Et propiolate, followed by amidation of the resulting triazolecarboxylate esters. The anticonvulsant activity of I depended on R and R1. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Synthetic Route of C7H5ClF2).
2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Synthetic Route of C7H5ClF2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics