Copper catalysed alkynylation of tertiary amines with CaC2 via sp3 C-H activation was written by Teong, Siew Ping;Yu, Dingyi;Sum, Yin Ngai;Zhang, Yugen. And the article was included in Green Chemistry in 2016.HPLC of Formula: 698-01-1 This article mentions the following:
A mild and easy-to-handle protocol to produce propargylamines with a terminal alkyne through catalytic cross-coupling of tertiary amines and calcium carbide was developed. The reaction proceeds via sp3 C-H bond activation and C-C coupling. Good to excellent yields were obtained for the corresponding propargylamines with both alkyl and aryl substitutions. The development of these functionalized propargylamines with a terminal alkyne group will offer a wider application for the synthesis of natural or pharmaceutical products due to their unique sp C-H reactivity. In the experiment, the researchers used many compounds, for example, 2-Chloro-N,N-dimethylaniline (cas: 698-01-1HPLC of Formula: 698-01-1).
2-Chloro-N,N-dimethylaniline (cas: 698-01-1) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.HPLC of Formula: 698-01-1
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics