Rearrangement in the Synthesis of Annulated Lactams Starting from Benzothiazines was written by Stalling, Timo;Saak, Wolfgang;Martens, Juergen. And the article was included in European Journal of Organic Chemistry in 2013.Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride This article mentions the following:
The conversion of methoxyamides I [R1 = R2 = Me, R1R2 = (CH2)5 R3 = H, Me, none, R4 = H, 3-Me, 3-MeO, 3-Cl, 2-NO2, X = (CH)n, n = 0, 1], based on iminic 1,4-benzothiazines, has led to three different products depending on the substitution pattern. On the one hand, different types of unknown lactam systems with and without a rearrangement under ring contraction of the benzothiazine substructure, e.g., tetracyclic lactams II, were selectively obtained. In this investigation, annulated lactams without ring contraction were formed by oxidation of the sulfide group to a sulfone group in the benzothiazine skeleton. On the other hand, benzothiazoles, which are oxidation products, were isolated. The structures of all types of lactams were verified by X-ray diffraction. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride).
2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Recommanded Product: 2-(3-Methoxyphenyl)acetyl chloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics