Visible Light-Promoted Sulfoxonium Ylides Synthesis from Aryl Diazoacetates and Sulfoxides was written by Lu, Juan;Li, Lei;He, Xiang-Kui;Xu, Guo-Yong;Xuan, Jun. And the article was included in Chinese Journal of Chemistry in 2021.Name: Methyl 2-chloro-2-phenylacetate This article mentions the following:
A visible light-promoted reaction of donor/acceptor diazoalkanes ArC(=N2)C(O)2R (R = CH3, CH(CH3)2, cyclobutyl, etc.) with sulfoxides R1S(O)R2 (R1 = Me, Ph; R2 = Me, Ph) towards the synthesis of synthetically useful sulfoxonium ylides ArC(=S(O)R1R2)C(O)2R was reported. The reaction occurred under sole visible light irradiation without the need of any transition-metals or additives, affording the corresponding sulfoxonium ylides in moderate to good yields. The success of late-stage modification of natural isolates or drug candidates, scale-up reaction and transformation of sulfoxonium ylides to other useful mols. further rendered the approach valuable. In the experiment, the researchers used many compounds, for example, Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6Name: Methyl 2-chloro-2-phenylacetate).
Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Name: Methyl 2-chloro-2-phenylacetate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics