Month: December 2022

Lu, Tong published the artcileDesign and synthesis of C-ring quinoxaline-substituted sinomenine 1,2,3-triazole derivatives via click reactions, Related Products of chlorides-buliding-blocks, the publication is Journal of Chemical Research (2020), 44(11-12), 699-704, database is CAplus.

The synthesis of C-ring quinoxaline-substituted sinomenine 1,2,3-triazole derivatives at the 4-OH via click reactions was accomplished, and a total of 16 novel sinomenine double N-heterocyclic derivatives are obtained in 74%-95% yields. The C-ring is first transformed into a 1,2-diketone structure under the action of hydrochloric acid, and then reacted with o-phenylenediamine to obtain a C-ring quinoxaline-substituted structure. The 4-OH of sinomenine reacted with chloropropyne to give an alkynyl sinomenine, and then reacts with sodium azide and various benzyl chlorides to give the target compounds All the synthesized derivatives were characterized by Fourier-transform IR spectrometry, high resolution mass spectrometry, ¹H NMR, and ¹³C NMR spectroscopy.

Journal of Chemical Research published new progress about 620-20-2. 620-20-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 3-Chlorobenzylchloride, and the molecular formula is C7H6Cl2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liang, Junqing published the artcileA bench-stable reagent for C-4 selective deuteriodifluoromethylation of azines, Formula: C12H15ClO3, the publication is Chinese Chemical Letters (2022), 33(11), 4817-4821, database is CAplus.

A bench-stable reagent, deuteriodifluoromethyl phosphine (DDFP) from cheap deuterium source for selectivity deuteriodifluoromethylation of azines with a high deuterium incorporation yield was reported. The late-stage modification of complex mols. further confirmed the potential of this reagent for practical applications. This reagent would be expected to find applications in synthesis of isotope-labeled mols. of interests for drug-discovery and related ilucidation of mechanism of action.

Chinese Chemical Letters published new progress about 637-07-0. 637-07-0 belongs to chlorides-buliding-blocks, auxiliary class Inhibitor,Cell Cycle,PPAR, name is Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate, and the molecular formula is C12H15ClO3, Formula: C12H15ClO3.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fu, Duo published the artcileMethanesulfinylation of Benzyl Halides with Dimethyl Sulfoxide, Related Products of chlorides-buliding-blocks, the publication is Journal of Organic Chemistry (2020), 85(4), 2752-2758, database is CAplus and MEDLINE.

A phenyltrimethylammonium tribromide-mediated nucleophilic substitution/oxygen transformation reaction of benzyl halides with DMSO has been developed. In this transition-metal-free reaction, DMSO acts as not only a solvent but also a “S(O)Me” source, thus providing a convenient method for the efficient and direct synthesis of various benzyl Me sulfoxides.

Journal of Organic Chemistry published new progress about 939-99-1. 939-99-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzyl chloride,Benzene, name is 1-(Chloromethyl)-4-(trifluoromethyl)benzene, and the molecular formula is C8H6ClF3, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fu, Duo published the artcileMethanesulfinylation of Benzyl Halides with Dimethyl Sulfoxide, Recommanded Product: 3-Chlorobenzylchloride, the publication is Journal of Organic Chemistry (2020), 85(4), 2752-2758, database is CAplus and MEDLINE.

A phenyltrimethylammonium tribromide-mediated nucleophilic substitution/oxygen transformation reaction of benzyl halides with DMSO has been developed. In this transition-metal-free reaction, DMSO acts as not only a solvent but also a “S(O)Me” source, thus providing a convenient method for the efficient and direct synthesis of various benzyl Me sulfoxides.

Journal of Organic Chemistry published new progress about 620-20-2. 620-20-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 3-Chlorobenzylchloride, and the molecular formula is C7H6Cl2, Recommanded Product: 3-Chlorobenzylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Ling published the artcileLuminescence-Driven Reversible Handedness Inversion of Self-Organized Helical Superstructures Enabled by a Novel Near-Infrared Light Nanotransducer, Product Details of C15H14Cl2S2, the publication is Advanced Materials (Weinheim, Germany) (2015), 27(12), 2065-2069, database is CAplus and MEDLINE.

Stimuli-directing self-organized supramol. architectures with desired properties provide the necessary thrust in the nanofabrication of intelligent mol. materials and devices. There have been only a few reports on using chiral photoresponsive mols. such as chiral azobenzenes,overcrowded alkenes,and chiral diarylethen as dopants for light-induced handedness inversion upon UV or visible-light irradiation After investigating the NIR-light-directed photoisomerization process of chiral switch (S, S)-8 and core-multishell nanotransducers in organic solvent, we examined the performance of the self-organized helical superstructures incorporated with the mol. switch and nanotransducers. Novel core-multishell UCNPs with dual wavelength NIR light transduction properties were rationally designed and synthesized by judiciously distributing the Tmn and Er3+ emissive ions in appropriate layers to furnish UV and visible luminescence on demand upon NIR irradiation at different wavelengths.

Advanced Materials (Weinheim, Germany) published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C8H11BO2, Product Details of C15H14Cl2S2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fujiwara, Yuta published the artcilePractical C-H Functionalization of Quinones with Boronic Acids, Product Details of C9H12BClO3, the publication is Journal of the American Chemical Society (2011), 133(10), 3292-3295, database is CAplus and MEDLINE.

A direct functionalization of a variety of quinones with several boronic acids has been developed. This scalable reaction proceeds readily at room temperature in an open flask using catalytic silver(I) nitrate in the presence of a persulfate co-oxidant. The scope with respect to quinones is broad, with a variety of alkyl- and arylboronic acids undergoing efficient cross-coupling. The mechanism is presumed to proceed through a nucleophilic radical addition to the quinone with in situ reoxidation of the resulting dihydroquinone. This method has been applied to complex substrates, including a steroid derivative and a farnesyl natural product.

Journal of the American Chemical Society published new progress about 480438-56-0. 480438-56-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is 3-Chloro-4-isopropoxyphenylboronic acid, and the molecular formula is C9H12BClO3, Product Details of C9H12BClO3.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Shostenko, A. G. published the artcileRadiational reaction of methyldichlorosilane with ethylene, Application In Synthesis of 14799-94-1, the publication is Khimiya Vysokikh Energii (1976), 10(2), 189-91, database is CAplus.

Radiochem. yields (mols./100 eV) were determined for MeSiCl2(C2H4)nH (n = 1, 2, 3), produced in the title reaction, at different reactant ratios. The activation energies of chain transfer and chain growth were practically equal.

Khimiya Vysokikh Energii published new progress about 14799-94-1. 14799-94-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(hexyl)(methyl)silane, and the molecular formula is C7H8BNO4, Application In Synthesis of 14799-94-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Kelgtermans, Hans published the artcileSynthesis of Functionalized Dioxa-aza[7]helicenes Using Palladium Catalyzed Arylations, Recommanded Product: 3-Chloro-4-fluoronitrobenzene, the publication is Organic Letters (2012), 14(6), 1500-1503, database is CAplus and MEDLINE.

Despite the recent reports on transition-metal catalyzed cycloisomerization strategies toward helicenes, the amount of palladium catalyzed routes remains rather scarce. Within this letter the successful preparation and characterization of novel dioxa-aza[7]helicenes using palladium mediated coupling reactions is presented.

Organic Letters published new progress about 350-30-1. 350-30-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Nitro Compound,Benzene, name is 3-Chloro-4-fluoronitrobenzene, and the molecular formula is C6H3ClFNO2, Recommanded Product: 3-Chloro-4-fluoronitrobenzene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Kelgtermans, Hans published the artcileA Fragment-Based Approach toward Substituted Trioxa[7]helicenes, HPLC of Formula: 350-30-1, the publication is Organic Letters (2012), 14(20), 5200-5203, database is CAplus and MEDLINE.

A series of novel substituted trioxa[7]helicenes have been successfully prepared by a one-pot palladium catalyzed C-H arylation reaction starting from readily prepared dibenzofuran fragments. The dinitro-substituted helicene I was analyzed by X-ray crystallog. revealing the occurrence of two distinct enantiomers in the asym. unit, which forms interesting supramol. motifs in the crystal, based on weak H-bonding interactions.

Organic Letters published new progress about 350-30-1. 350-30-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Nitro Compound,Benzene, name is 3-Chloro-4-fluoronitrobenzene, and the molecular formula is C6H3ClFNO2, HPLC of Formula: 350-30-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liu, Yuhua published the artcileMechanistic insights into the palladium-catalyzed hydroaminocarbonylation of alkenes, SDS of cas: 1375325-77-1, the publication is New Journal of Chemistry (2021), 45(17), 7516-7522, database is CAplus.

DFT calculations have been conducted on Pd-catalyzed regioselective hydroaminocarbonylation of alkenes. The favored path I consists of styrene insertion, CO insertion, and nucleophilic attack, which is the rate determining step. In the PPh₃-assisted system, the conjugation between the benzylic units and the acyl group stabilizes the branched transition state in the nucleophilic attack leading to the branched selectivity. On the other hand, in the xantphos-assisted system, the steric repulsion between the substrate and the ligand leads to a higher barrier for the branched transition state; therefore, linear selectivity is favored which is in line with the exptl. observation. The anal. of the electronic and steric effects of ligands on the selectivity helps to develop a catalyst for hydroaminocarbonylation of alkenes.

New Journal of Chemistry published new progress about 1375325-77-1. 1375325-77-1 belongs to chlorides-buliding-blocks, auxiliary class Palladium, name is Chloro[(4,5-bis(diphenylphosphino)-9,9-dimethylxanthene)-2-(2-amino-1,1-biphenyl)]palladium(ii), and the molecular formula is C51H42ClNOP2Pd, SDS of cas: 1375325-77-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics