A synthesis of functionalized 2-imino-1,3-thiazoles from tetramethylguanidine, isothiocyanates, and 2-chloro-1,3-dicarbonyl compounds was written by Yavari, Issa;Malekafzali, Alaleh;Seyfi, Samereh. And the article was included in Journal of the Iranian Chemical Society in 2014.Computed Properties of C7H3Cl2NS This article mentions the following:
Synthesis of functionalized 2-imino-1,3-thiazoles I [R1 = Et, Ph, PhCO, 4-FC6H4, etc.; R2 = Me, OEt] via Hantzsch method modified by the reaction of 2-chloro-1,3-dicarbonyl compounds with 2-(amidosulfanylenemethyl)-1,1,3,3-tetramethylguanidines (prepared in situ from tetramethylguanidine and isothiocyanates) were reported. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Computed Properties of C7H3Cl2NS).
2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Computed Properties of C7H3Cl2NS
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics