Synthesis and Antimicrobial Evaluation of Calycanthaceous Alkaloid Derivatives was written by Yang, Cheng;Zheng, Shaojun;Tan, Yi;Chen, Xiaoyun;Bai, Hongjin;Zhu, Rui;Gao, Yuhua. And the article was included in Chemistry of Natural Compounds in 2021.Safety of 1-(Chloromethyl)-3-methylbenzene This article mentions the following:
To find pesticidal lead compounds with high activity, a series of new chimonanthine derivatives was synthesized via the introduction of the functional group at the N-position to compound I. A preliminary bioassay showed that most of them displayed potent bioactivities. In particular, compound II displayed significant activity and might be a potential novel lead compound for further development of antifungal agent. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Safety of 1-(Chloromethyl)-3-methylbenzene).
1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Safety of 1-(Chloromethyl)-3-methylbenzene
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics