The Effects of Substituents on the Geometry of π-π Interactions was written by Snyder, Seth E.;Huang, Bin-Syuan;Chu, Yu W.;Lin, Huei-Shian;Carey, James R.. And the article was included in Chemistry – A European Journal in 2012.HPLC of Formula: 1711-11-1 This article mentions the following:
The authors have designed and used a simple mol. recognition system to study the substituent effects in aromatic interactions. Recently, 3- and 3,5-disubstituted benzoyl leucine diethylamides with aromatic rings of varying electronic character organized into homochiral dimers in the solid state through a parallel displaced π-π interaction and two hydrogen bonds, but no such homochiral dimerization was observed for the unsubstituted case. This phenomenon supports the hypothesis that substituents stabilize π-π interactions regardless of their electronic character. To further study the origin of substituent effects for π-π interactions, the authors synthesized and crystallized 4-substituted benzoyl leucine diethylamides. Surprisingly, only two of the 4-substituted compounds formed homochiral dimers. A comparison among the 4-substituted compounds that crystallized as homochiral dimers and their 3-substituted counterparts revealed that there are differences in regard to the geometry of the aromatic rings with respect to each other, which depend on the electronic nature and location of the substituent. The crystal structures of the homochiral dimers that showed evidence of direct, local interactions between the substituents on the aromatic rings also displayed nonequivalent dihedral angles in the individual monomers. The crystallog. data suggests that such flexing may be the result of the individual mols. orienting themselves to maximize the local dipole interactions on the resp. aromatic rings. The results presented here can potentially have broad applicability towards the development of mol. recognition systems that involve aromatic interactions. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1HPLC of Formula: 1711-11-1).
3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.HPLC of Formula: 1711-11-1
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics