Fengycin A analogs with enhanced chemical stability and antifungal properties was written by Gimenez, Diana;Phelan, Aoife;Murphy, Cormac D.;Cobb, Steven L.. And the article was included in Organic Letters in 2021.Formula: C19H15Cl This article mentions the following:
Fengycins are cyclic lipo-depsipeptides produced by Bacillus spp. that display potent antifungal properties but are chem. unstable. This instability has meant that no total synthesis of any fengycin has been published. Here we report the synthesis of fengycin A analogs that display enhanced antifungal properties and chem. stability under both basic and acidic conditions. The analogs prepared also demonstrate that the fengycin core structure can be modified and simplified without the loss of antifungal activity. In the experiment, the researchers used many compounds, for example, (Chloromethanetriyl)tribenzene (cas: 76-83-5Formula: C19H15Cl).
(Chloromethanetriyl)tribenzene (cas: 76-83-5) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Formula: C19H15Cl
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics