Iron(III) triflate as a highly efficient, recyclable and green catalyst for the N-Boc protection of amines was written by Feng, Chengliang;Chu, Ningning;Zhang, Shuguang;Cai, Jin;Chen, Junqing;Hu, Huayou;Ji, Min. And the article was included in Journal of Chemical Research in 2013.Recommanded Product: tert-Butyl (4-chlorophenyl)carbamate This article mentions the following:
Iron(III) triflate was used as an efficient catalyst for N-t-butoxycarbonylation of amines with di-t-Bu dicarbonate under solvent-free conditions at room temperature Various aliphatic, aromatic, heterocyclic amines and aminols were protected as their corresponding mono-carbamates in excellent yields and short reaction times. Only two of the 23 monocarbamates were new. No competitive side reactions such as isocyanate, urea, nor N,N-di-Boc formation were observed The reported method is mild and has the advantages of low cost, chemoselectivity and, because no solvent is used and the catalyst can be recycled, it is classifiable as a green procedure. In the experiment, the researchers used many compounds, for example, tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6Recommanded Product: tert-Butyl (4-chlorophenyl)carbamate).
tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Recommanded Product: tert-Butyl (4-chlorophenyl)carbamate
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics