Covalent addition of N-chlorosaccharin to cyclohexene was written by Dawn, Hanson;Pitman, Ian H.;Higuchi, Takeru. And the article was included in Journal of Pharmaceutical Sciences in 1970.Application of 14070-51-0 This article mentions the following:
N-(2-Chlorocyclohexyl)-saccharin (I), m. 171-2.5° [Me2CO-H2O), was prepared by adding 400 mg N-chlorosaccharin (II) to 15 ml I at 25° . The structure was confirmed by NMR and ir spectroscopy, and elemental anal. In the experiment, the researchers used many compounds, for example, 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0Application of 14070-51-0).
2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Application of 14070-51-0
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics